Job Opportunities

Pre-Clinical VP (China/US)

Department: Pre-Clinical
Job Title: Pre-Clinical VP
Report to: CMO
Location: China/US

MAIN REPONSIBILITIES:

  • Design and execute preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of drug candidates.
  • Manage CROs/Academic sites in the conduct of in vitro and in vivo ADME studies.
  • Responsible for the analysis, interpretation, integration, and reporting of preclinical DMPK data generated with CROs; Lead efforts for IND and NDA/BLA filings.
  • Work closely with business development group to evaluate external opportunities.
  • Build close relationships with partner functions and therapeutic areas.
  • Evaluate and implement novel technologies to characterize the disposition and clearance mechanisms of new chemical entities.

QUALIFICATIONS:

  • Ph.D. in Pharmacokinetics, Pharmacology, Pharmaceutics or other relevant field with over 10 years of experience in biopharmaceutical industry, with evidence of drug development experience is preferred.ß
  • Strong knowledge of drug metabolism, ADME concepts, PK, PD and bioanalytical principles is required.
  • Experience working with CROs to deliver on radiolabeling ADME studies, including rat QWBA, human ADME, and metabolite ID experiments
  • Experience working through IND to NDA package submission, Oncology project preferred.
  • Excellent oral and written English.